Systematic review reveals inconsistent associations between DNA repair gene polymorphisms and ototoxicity, indicating a need for larger studies.
Although several DNA repair gene polymorphisms have been explored, findings remain inconsistent and limited by populations and SNPs studied. Larger, well-designed studies with standardized methodologies are needed to confirm these associations and identify genetic markers for predicting high-risk patients for CIO.
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Omar et al. (2026) studied this question.
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