Molecular engineering of aggregation-induced emission enhanced photosensitizers to boost the theranostic performance in photodynamic therapy

Key Points

• This research aims to enhance the performance of photosensitizers in photodynamic therapy by utilizing molecular engineering techniques.
• Fabrication of TPEPyTMB-3 nanoparticles
• Targeting mitochondria
• Evaluation in hypoxic conditions
• Enhanced aggregation-induced emission observed
• Improved therapeutic response in targeted photodynamic therapy
• Potential increase in effectiveness under low oxygen environments