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January 17, 2026Operative Neurosurgery

Implantable Pulse Generator Site Pain Following Spinal Cord Stimulation: A Case-Control Study

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Authors

JLJordan L. W. LamKLKyle J. LoiVVVarsha Vedapudi

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Implication

A case-control study investigates risk factors for pain at the implantable pulse generator site in individuals with spinal cord stimulation, suggesting implications for treatment.

Key Points

  • To investigate factors associated with implantable pulse generator site pain (IPGSP) following spinal cord stimulation procedures.
  • Performed a search using current procedural terminology codes for patients receiving spinal cord stimulation from January 2000 to February 2021.
  • Conducted a retrospective chart review to identify cases of IPGSP.
  • Collected and compared demographic, medical, and surgical data of cases with age- and gender-matched controls.
  • Of 615 patients, 29 had surgery due to IPGSP.
  • IPGSP cases were younger (mean age 47.2 years) and predominantly female (76%) compared to controls (mean age 51.2 years, 52% female).
  • No significant associations were found between IPGSP and other demographic or medical factors after controlling for age and gender.

Cite This Study

Lam et al. (2026) studied this question.

synapsesocial.com/papers/696b2631d2a12237a9349711https://doi.org/10.1227/ons.0000000000001914
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Supporting information retrieval from electronic health records: A report of University of Michigan’s nine-year experience in developing and using the Electronic Medical Record Search Engine (EMERSE)2015 · 452 citations
  2. 2Chronic pain: One year prevalence and associated characteristics (the HUNT pain study)2013 · 104 citations
  3. 3Real-World Cost-Effectiveness Analysis of Spinal Cord Stimulation vs Conventional Therapy in the Management of Failed Back Surgery Syndrome2021 · 18 citations
  4. 4Matching Cases and Controls Using SAS® Software2019 · 29 citations
  5. 5Systematic review and meta-analysis of placebo/sham controlled randomised trials of spinal cord stimulation for neuropathic pain2019 · 136 citations