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January 17, 2026Materials Horizons7 citations

Bioadhesive Polydopamine-Vitamin A Derivative Hydrogels Reprogram the Wound Microenvironment for Scarless Wound Healing and Hair Follicle Regeneration

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KWKang WangHZHengjie ZhangMWMengxin Wang

Key Points

  • The study aims to explore the effectiveness of bioadhesive polydopamine-vitamin A derivative hydrogels in promoting scarless wound healing and hair follicle regeneration.
  • Developed bioadhesive hydrogels combining polydopamine and vitamin A derivatives
  • Tested hydrogels in controlled environments affecting skin wound healing
  • Assessed the microenvironment's response to treatment for enhanced regeneration
  • Hydrogels significantly improved the healing process compared to standard treatments
  • Promoted the regeneration of hair follicles, indicating potential for hair neogenesis
  • Microenvironment alterations were conducive to scarless healing

Abstract

Achieving scarless healing combine with skin appendage regeneration remains an extremely challenging task in the treatment of skin wounds. Vitamin A derivatives have shown great potential for follicle neogenesis and...

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/696b2672d2a12237a9349c15https://doi.org/10.1039/d5mh02076j
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