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The research aims to understand how LARGE1 regulates grain size in rice by interacting with PGL2 and APG.

January 18, 2026The Plant JournalOpen Access

The LARGE1 controls grain size by repressing the interaction between PGL2 and APG in rice

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The research aims to understand how LARGE1 regulates grain size in rice by interacting with PGL2 and APG.
Biochemical analyses to assess protein interactions
Genetic evidence supporting interactions among LARGE1, PGL2, and APG
RNA-seq analyses to evaluate transcriptional activity
LARGE1 represses the formation of the PGL2/APG heterodimer
PGL2 positively influences grain size by interacting with APG
Evidence shows that LARGE1 and PGL2 work in a common regulatory pathway affecting grain size

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Uncovers LARGE1's role in regulating grain size in rice, highlighting its potential for crop breeding.

Liu et al. (2026) studied this question.

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