Key result
SAVR within three months post-stroke is linked to increased recurrent stroke and MACE risk.
Why the study?
Does the timing of aortic valve replacement surgery after a previous stroke affect the risk of recurrent stroke and mortality in patients undergoing SAVR?
Does the timing of aortic valve replacement surgery after a previous stroke affect the risk of recurrent stroke and mortality in patients undergoing SAVR?
Performing surgical aortic valve replacement less than 3 months after a previous stroke is associated with a significantly higher risk of recurrent ischemic stroke and MACE.
May warrant delaying SAVR >3 months post-stroke; leaves open optimal timing in prospective trials.
Previous stroke is a major risk factor of recurrent ischemic stroke and MACE in patients undergoing SAVR, especially if time elapsed between previous stroke and surgery is less than 3 months.
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Andreasen et al. (2018) studied this question. SAVR performed within 3 months after a previous stroke is associated with increased risk of recurrent ischemic stroke and MACE.