Associations of nutritional risk, pre-treatment malnutrition, and cachexia with mortality, local recurrence, and metastasis in head and neck cancer: a five-year prospective cohort study

Key Points

• To investigate the impact of pre-treatment nutritional risk, malnutrition, and cachexia on mortality and cancer outcomes in head and neck cancer patients.
• Conducted a five-year prospective cohort study
• Assessed nutritional risk and malnutrition using GLIM and PG-SGA
• Measured outcomes including mortality, local recurrence, and metastasis
• Nutritional risk was significantly associated with all three outcomes: mortality, local recurrence, and metastasis
• The PG-SGA score over 16 was crucial for predicting these outcomes
• Suggests combining PG-SGA and cachexia assessments for better predictions