What question did this study set out to answer?

The study aims to evaluate the antioxidant capacity and antidiabetic effects of Aristolochia longa extracts in a diabetic model.

January 20, 2026

Phenolic Profile, Antioxidant Potential, and Antidiabetic Effects of Aristolochia longa Extracts in Streptozotocin-Induced Diabetic Rats.

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Authors

IBIkram BenahmedUniversité Djilali de Sidi Bel Abbès MBMokhtar BenabderrahmaneUniversité Djilali de Sidi Bel Abbès HMHouria MedjdoubUniversity of Abou Bekr Belkaïd

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Implication

This research evaluates the antidiabetic and antioxidant effects of Aristolochia longa extracts in diabetic rats, indicating potential health benefits.

Key Points

The study aims to evaluate the antioxidant capacity and antidiabetic effects of Aristolochia longa extracts in a diabetic model.
Conducted antioxidant assays using DPPH, β-carotene, and ferric reducing power methods.
Analyzed phytochemical composition through high-performance liquid chromatography.
Conducted in vivo studies with diabetic rats using hydromethanolic extracts at doses of 250 and 500 mg/kg.
Performed oral glucose tolerance tests to assess glucose-lowering effects.
Extracts showed strong antioxidant activity with specific IC<sub>50</sub> values for various assays.
Demonstrated significant α-amylase inhibition with an IC<sub>50</sub> of 0.470 ± 0.06 mg/mL.
Blood glucose levels were significantly reduced after 14 and 21 days of treatment in diabetic rats.
Extracts improved lipid profile parameters, exhibiting an antilipidemic effect.

Cite This Study

Benahmed et al. (2026) studied this question.

synapsesocial.com/papers/696f1a239e64f732b51ee758 https://doi.org/10.1002/cbdv.202502659

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Implication

This research evaluates the antidiabetic and antioxidant effects of Aristolochia longa extracts in diabetic rats, indicating potential health benefits.

Phenolic Profile, Antioxidant Potential, and Antidiabetic Effects of Aristolochia longa Extracts in Streptozotocin-Induced Diabetic Rats.

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Implication

Key Points

Cite This Study

Phenolic Profile, Antioxidant Potential, and Antidiabetic Effects of Aristolochia longa Extracts in Streptozotocin-Induced Diabetic Rats.

Discussion

Member takes

Implication

Key Points

Cite This Study

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