What question did this study set out to answer?

To analyze the molecular characteristics of Aujeszky's disease in a hunting dog that consumed infected meat.

January 20, 20260 citations

Tracking Pseudorabies: a case description in an Italian Hunting Dog.

DGDomenico GalanteIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata SCStefano CastellanaIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata APAntonio PetrellaIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata

Key Points

To analyze the molecular characteristics of Aujeszky's disease in a hunting dog that consumed infected meat.
Observed clinical symptoms of terminal illness after meat consumption.
Performed necropsy at the Experimental Zooprophylactic Institute.
Conducted histological analysis and genome sequencing.
SuHV-1 DNA was detected in the dog's brain tissue.
Virus isolation was successfully achieved using Vero cells.
Meningoencephalitis presented as a key histological feature.
Identified genome matched a unique previously reported strain from another hunting dog in Italy.

Abstract

This study investigated the molecular features of Aujeszky's disease in a hunting dog from southern Italy. After consuming meat from infected wild boars, a 5-year-old male dog developed intense itching and died within 48 hours. Pseudorabies was suspected and necropsy was performed at the Experimental Zooprophylactic Institute of Apulia and Basilicata. SuHV-1 DNA was detected in the brain tissue, and the virus was isolated using Vero cells. Histological features and the analysis of genome sequencing revealed a non-suppurative meningoencephalitis caused by Aujeszky's disease. The yielded genome corresponded to a previously reported and unique genome (KU198433) isolated from a hunting dog in Italy. These findings improve understanding of pseudorabies's molecular epidemiology and help assess its epizootic potential.

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