Observes the relationship between patent foramen ovale and distinct features of pyogenic brain abscess, suggesting specific implications for diagnosis.
Patent foramen ovale (PFO) has a prevalence of ∼25%. Its association with pyogenic brain abscess (PBA) is unclear. We reviewed adults with PBA and known PFO status from 1/1/2009-12/31/2021 at Mayo Clinic. High PFO prevalence (40.5%) was seen. PBA patients with PFO had distinct abscess characteristics but unchanged one-year, all-cause mortality.
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Abu-Zeinah et al. (2026) studied this question.
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