Fetal growth restriction and preeclampsia as endpoints of a spectrum from the viewpoint of placental histopathology

Key Points

• The research aims to differentiate histopathological profiles of preeclampsia and fetal growth restriction to understand prognostic implications.
• Analysis of placental tissue samples from pregnancies with preeclampsia and fetal growth restriction.
• Comparison of histopathological features like vascular development and placental structure.
• Identification of characteristic patterns associated with preeclampsia and fetal growth restriction.
• Placental profile of preeclampsia shows inadequate vascular development and decidual vasculopathies.
• Fetal growth restriction is marked by undercapillarization of the placental villous tree and villitis of unknown etiology.
• Distinct histopathological features indicate different prognoses for preeclampsia and fetal growth restriction.