Key result
The Resting Full-cycle Ratio (RFR) is diagnostically equivalent to iFR and better detects significant coronary stenoses throughout the entire cardiac cycle.
Why the study?
Does Resting Full-cycle Ratio (RFR) provide diagnostic equivalence to iFR in detecting physiologically significant coronary stenoses?
Does Resting Full-cycle Ratio (RFR) provide diagnostic equivalence to iFR in detecting physiologically significant coronary stenoses?
RFR is a valid non-hyperemic index that is diagnostically equivalent to iFR but evaluates the full cardiac cycle, potentially identifying significant stenoses missed by segment-specific assessments.
RFR may expand resting index options in labs; leaves open prospective outcome validation.
RFR is diagnostically equivalent to iFR but unbiased in its ability to detect the lowest Pd/Pa during the full cardiac cycle, potentially unmasking physiologically significant coronary stenoses that would be missed by assessment dedicated to specific segments of the cardiac cycle.
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Svanerud et al. (2018) studied this question. The Resting Full-cycle Ratio (RFR) is diagnostically equivalent to iFR and better detects significant coronary stenoses throughout the entire cardiac cycle.
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