Key result
Bariatric surgery is linked to a ~12% reduction in LVMI among patients with obesity.
Why the study?
Obesity causes adverse cardiac structural and haemodynamic changes, and evidence suggests bariatric surgery may improve cardiac structure and function.
Does bariatric surgery improve cardiac structure and function in patients with obesity?
Systematic Review (n=3,332)
Does bariatric surgery improve cardiac structure and function in patients with obesity?
Effect estimate: null (95% CI 0.096-0.149)
p-value: p=<0.001
Bariatric surgery induces significant reverse cardiac remodeling and improves both systolic and diastolic function, highlighting its cardiovascular benefits in severe obesity.
Supports bariatric surgery for reverse remodeling in obesity; reinforces prior observational evidence in larger meta-analysis.
Introduction Obesity is associated with alterations in cardiac structure and haemodynamics leading to cardiovascular mortality and morbidity. Culminating evidence suggests improvement of cardiac structure and function following bariatric surgery. Objective To evaluate the effect of bariatric surgery on cardiac structure and function in patients before and after bariatric surgery. Methods Systematic review and meta-analysis of studies reporting pre- and postoperative cardiac structure and function parameters on cardiac imaging in patients undergoing bariatric surgery. Results Eighty studies of 3332 patients were included. Bariatric surgery is associated with a statistically significant improvement in cardiac geometry and function including a decrease of 12.2% (95% CI 0.096–0.149; p < 0.001) in left ventricular (LV) mass index, an increase of 0.155 (95% CI 0.106–0.205; p < 0.001) in E/A ratio, a decrease of 2.012 mm (95% CI 1.356–2.699; p < 0.001) in left atrial diameter, a decrease of 1.16 mm (95% CI 0.62–1.69; p < 0.001) in LV diastolic dimension, and an increase of 1.636% (95% CI 0.706–2.566; p < 0.001) in LV ejection fraction after surgery. Conclusion Bariatric surgery led to reverse remodelling and improvement in cardiac geometry and function driven by metabolic and haemodynamic factors.
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Sargsyan et al. (2023) conducted a systematic review in Obesity (n=3,332). Bariatric Surgery was evaluated on Left ventricular mass index (LVMI) (null, 95% CI 0.096-0.149, p=<0.001). Bariatric surgery is associated with a statistically significant decrease of 12.2% in left ventricular mass index compared to pre-operative measurements in patients with obesity.
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