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Reusable Fluorescent Biosensor Based on Morphology-controlled ZIF-8⊃FAM-DNA film | Synapse

January 22, 2026

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Reusable Fluorescent Biosensor Based on Morphology-controlled ZIF-8⊃FAM-DNA film

LWLi‐Jun WanUniversity of California, Riverside DRDongjun RenNorthwestern University YLYangyi LiuNanjing University of Posts and Telecommunications

Key Points

The aim is to develop a reusable ZIF-8⊃FAM-DNA film for effective biosensing applications.
Synthesis of ZIF-8 with controlled morphology
Incorporation of FAM-DNA into ZIF-8 matrix
Assessment of film reusability in biosensing applications
The ZIF-8⊃FAM-DNA film shows significant fluorescence response to target analytes
Demonstrates multiple reuse cycles without loss of sensitivity
Shows potential as a reliable biosensing platform

Abstract

As a promising porous material, zeolitic imidazolate framework-8 (ZIF-8) exhibits significant application potential in biosensing. However, its reusability in solution form is limited. In this work, a reusable ZIF-8⊃FAM-DNA film...

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Cite This Study

Wan et al. (Thu,) studied this question.

synapsesocial.com/papers/6971bd90642b1836717e2414 https://doi.org/https://doi.org/10.1039/d6an00017g