Ultrasound activated bowl-like nanomotors release nitric oxide for enhanced thrombus therapy

Key Points

• The research aims to improve thrombolytic therapy by utilizing ultrasound-activated nanomotors to release nitric oxide.
• Developed bowl-like nanomotors with asymmetric morphology.
• Applied sonodynamic therapy to activate the nanomotors.
• Examined the effects of released nitric oxide on thrombus dissolution.
• Enhanced mobility of nanomotors improves thrombolytic efficiency.
• Significant release of nitric oxide correlates with increased thrombus therapy effectiveness.
• Integration of sonodynamic therapy shows promising results in thrombolysis outcomes.