January 22, 2026Diabetologia0 citationsOpen Access

Beta cell function and mass in individuals with and without remission of type 2 diabetes after Roux-en-Y gastric bypass

STSevilay TokgözRadboud University Nijmegen LDLaura N. Deden AHAdrianne Hofboer

Key Result

Individuals with remission of type 2 diabetes post-Roux-en-Y gastric bypass exhibited improved beta cell function and mass compared to those without remission.

Key Points

The research aims to compare beta cell function and mass in individuals with and without remission of type 2 diabetes following Roux-en-Y gastric bypass.
Conducted a clinical trial involving individuals undergoing Roux-en-Y gastric bypass
Measured beta cell function and mass pre- and post-surgery
Assessed remission status of type 2 diabetes in participants
Individuals in remission showed improved beta cell function
Beta cell mass differed significantly between groups post-surgery
Enhanced insulin sensitivity was correlated with remission status

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

ClinicalTrials.gov NCT02542059.

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Cite This Study

Tokgöz et al. (Tue,) reported a other. Individuals with remission of type 2 diabetes post-Roux-en-Y gastric bypass exhibited improved beta cell function and mass compared to those without remission.

synapsesocial.com/papers/6971be2c642b1836717e2cca https://doi.org/https://doi.org/10.1007/s00125-025-06659-1