Twenty Years of Microfluidic Probes and Open-Space Microfluidics: From Origins to Emerging Directions

Dima Ali; Ayoub Glia; Mohammad A. Qasaimeh

doi:10.1039/d5lc00879d

January 1, 2026Lab on a Chip

Twenty Years of Microfluidic Probes and Open-Space Microfluidics: From Origins to Emerging Directions

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Key Points

The aim is to review the developments in microfluidic probes and their applications in fluid handling on biointerfaces.
Literature review of microfluidic probe innovations
Analysis of hydrodynamic flow confinement techniques
Evaluation of applications in biological contexts
Microfluidic probes show enhanced fluid delivery capabilities on biological surfaces.
Open-space microfluidics allows for contact-free manipulation of fluids.
Emerging applications indicate potential for diagnostics and therapeutics.

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Implication

This review explores advancements in microfluidic probes for precise fluid manipulation on biological surfaces, suggesting future research paths.

Abstract

Microfluidic probes (MFPs) are an emerging class of open microfluidic devices that use hydrodynamic flow confinement (HFC) to enable precise, contact-free delivery and removal of fluids on biological surfaces. Unlike...

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Ali et al. (2026) studied this question.

synapsesocial.com/papers/6971be2c642b1836717e2d8e https://doi.org/10.1039/d5lc00879d

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Twenty Years of Microfluidic Probes and Open-Space Microfluidics: From Origins to Emerging Directions

Key Points

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Abstract

Discussion

Cite This Study

Twenty Years of Microfluidic Probes and Open-Space Microfluidics: From Origins to Emerging Directions

Key Points

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Implication

Abstract

Discussion

Cite This Study

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