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Large cohorts demonstrate that social-media exposure correlates with cortical thinning in adolescents, suggesting modifiable risk factors.
Large 2025 adolescent cohorts combining high-resolution MRI with epigenomic profiling now demonstrate that excessive social-media exposure correlates with early cortical thinning signals, neuroinflammatory promoter activation, and impaired attention-executive network maturation. These effects are linked to microglial cytokine priming and activity-dependent chromatin stress rather than structural neurodevelopmental disorders. Emerging data suggest modifiable risk windows through behavioral restriction modeling and inflammation-calming drug-neutral adjuncts without disrupting digital literacy frameworks.
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Batool et al. (2026) studied this question.
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