Pharmacological treatments like hormone replacement therapy and SSRIs were effective for hot flashes and mood symptoms in African American women, though tailored evidence is limited.
Are pharmacological and holistic treatments effective for managing menopause symptoms in African American women aged 40-65?
While pharmacological treatments like hormone replacement therapy and SSRIs are effective for menopause symptoms, there is a significant lack of tailored evidence and race-specific reporting for African American women.
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African American (AA) women often experience earlier onset and more severe menopause symptoms, especially vasomotor symptoms (VMSs) like hot flashes, compared to other groups. However, limited research has examined the effectiveness and acceptability of menopause treatments in this population. This scoping review synthesized evidence on pharmacological (e.g., hormone replacement therapy HRT, SSRIs, venlafaxine, nitroglycerin) and holistic (e.g., dietary changes, physical activity PA, supplementation) approaches for managing menopause symptoms in AA women. Using Joanna Briggs Institute and PRISMA-ScR guidelines, a scoping review was conducted, guided by the PCC framework. Four databases (CINAHL, PsycInfo, PubMed, Scopus) were searched for English-language studies (2010–2025) involving AA women aged 40–65. Eligible studies included RCTs and observational designs with ≥10% AA participants. Data were charted and synthesized descriptively. Fourteen U.S.-based studies (11–53% AA representation) were included. Pharmacological treatments—especially HRT and SSRIs—were effective for VMSs and mood symptoms. Holistic approaches showed mixed outcomes; PA and magnesium offered modest benefit, while phytoestrogens sometimes worsened memory. Race-specific results were rarely reported. Effective pharmacological options exist, but evidence tailored to AA women is lacking. Future research must ensure greater AA representation and culturally responsive approaches to menopause care.
Amanzai et al. (Tue,) reported a other. Pharmacological treatments like hormone replacement therapy and SSRIs were effective for hot flashes and mood symptoms in African American women, though tailored evidence is limited.