Epigenetic Age Versus Chronologic Age in Adult Spinal Deformity Surgery: A Prospective Cohort Study.

Key Points

• This research aims to examine the relationship between epigenetic age and postoperative complications in spinal deformity surgery patients.
• Conducted a prospective cohort study
• Measured epigenetic age and chronologic age in adult spinal deformity patients
• Analyzed postoperative complications in relation to age types
• Postoperative complications were correlated with elevated epigenetic age compared to chronologic age
• Epigenetic age showed potential as a biomarker for preoperative risk assessment