Nationwide registry study reveals high anaemia prevalence and its association with disease activity in paediatric-onset inflammatory bowel disease.
Key Points
This study investigates the prevalence and types of anaemia at diagnosis and during the following five years in pediatric-onset inflammatory bowel disease.
Identified PIBD patients aged 6-17 from nationwide registers between 2014-2022.
Retrieved biochemical data from Clinical Laboratory Information Register.
Defined anaemia using WHO criteria and classified subtypes based on specific laboratory results.
Calculated relative risks to compare the risk of anaemia between different patient characteristics.
660 out of 1266 patients (52.1%) were anaemic at diagnosis.
The most common anaemia subtype was a combination of iron deficiency anaemia and anaemia of chronic disease (64%).
Higher anaemia risk was observed in girls (RR: 1.2) and Crohn’s disease patients (RR: 1.2).
Anaemia prevalence decreased over time but was associated with disease activity.