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January 23, 2026Journal of Crohn s and Colitis0 citations

P0405The Influence of Psychological support in Patients with Ulcerative Colitis for Adherence to Drug Therapy

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AGA GorodetskayaMoscow Clinical Scientific CenterLFL.D. FirsovaMoscow Clinical Scientific CenterOKO KnyazevMoscow Clinical Scientific Center

Key Points

  • This study aims to evaluate how psychological support affects drug therapy adherence in patients with ulcerative colitis.
  • Conducted questionnaires assessing adherence to drug therapy among 1000 patients with ulcerative colitis.
  • Re-interviewed 874 patients six months after initial assessment.
  • Psychological support sessions included diagnostic and correctional classes by a medical psychologist.
  • 56.9% of re-interviewed patients had low adherence to drug therapy.
  • Among patients with psychological support, adherence increased by 22.48%.
  • 62.2% of patients receiving psychological support had high adherence post-intervention.
  • In the absence of psychological support, the adherence increase was only 8.8%.

Abstract

Abstract Background Psychological support for patients with Ulcerative Colitis (UC) in the Department of inflammatory bowel diseases (IBD) was provided by a medical psychologist who, in training sessions, helped patients with UC to cope with the effects of the disease on general well-being and condition, and also identified psychoemotional moments that could affect the course of the disease. A medical psychologist conducted diagnostic and correctional classes in the department, predicting possible risks of deterioration of the patient’s psychological state. Objective: to evaluate the effect of psychological support in patients with ulcerative colitis on adherence to drug therapy. Methods 1000 patients with UC who underwent a questionnaire to assess adherence to drug therapy, 874 (87.4%) patients were re-interviewed after 6 months after discharge from the hospital. A medical psychologist conducted diagnostic and correctional classes in the department, predicting possible risks of deterioration of the patient’s psychological state. Results Among the 874 patients who underwent repeated questioning, 498 (56.9%) had low adherence to drug therapy. 180 (20.6%) patients with UC with low adherence to drug therapy had psychological support, 318 (79.4%) patients from the low-adherence group did not have psychological support. According to a repeated survey of patients with UC in the group with psychological support, the level of adherence increased by 22.48%. 112 (62.2%) patients according to the Morisky-Green questionnaire had high adherence to drug therapy after remedial sessions with a medical psychologist, 68 (37.8%) patients with UC maintained low adherence to drug therapy. In the group of patients without psychological support, according to repeated questionnaires, the level of adherence increased by 8.8%: out of 318 patients, only 44 (13.8%) increased their adherence to drug therapy, while 274 (86.2%) maintained low adherence to drug therapy (OR - 10.108; 95% CI - 6.527- 15.654; x2 - 122.848; p 0.001) Conclusion Psychological support in patients with ulcerative colitis increases adherence to drug therapy after 6 months of follow-up. Conflict of interest: Gorodetskaya, Anait: No conflict of interest Firsova, Lyudmila: No conflict of interest Prof. Knyazev, Oleg: No conflict of interest Kagramanova, Anna Valeryevna: No conflict of interest

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Cite This Study

Gorodetskaya et al. (2026) studied this question.

synapsesocial.com/papers/69730f18c8125b09b0d1ee13https://doi.org/10.1093/ecco-jcc/jjaf231.586
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