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January 23, 2026The Analyst

Targeted Serum Metabolomics Reveals Alterations in Amino Acid and Neurotransmitter Pathways in Parkinson's Disease

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Authors

JYJiaxin YangDWDong WuZWZhiwei Wang

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Overview

Metabolomic profiling reveals altered amino acid and neurotransmitter levels in Parkinson's disease, suggesting metabolic dysregulation.

Key Points

  • This research aims to explore serum metabolomic alterations in amino acid and neurotransmitter pathways in Parkinson's disease.
  • Utilized targeted metabolomics to profile serum metabolites.
  • Selected specific amino acids and neurotransmitters for analysis.
  • Compared metabolomic profiles between individuals with Parkinson's disease and controls.
  • Identified significant alterations in amino acid levels in Parkinson's disease.
  • Noted changes in key neurotransmitter pathways associated with disease progression.
  • Correlated metabolomic changes with clinical symptoms and disease markers.

Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/69730f78c8125b09b0d1f509https://doi.org/10.1039/d5an00961h
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