This research aims to explore how specific serum biomarkers relate to psychosis in Alzheimer disease.
Cohort study design
Analysis of serum concentrations of hyperphosphorylated tau and neurofilament light chain
Focus on patients with psychosis and neuropsychiatric impairment
Elevated levels of hyperphosphorylated tau are associated with psychosis
Neurofilament light chain concentrations correlate with broader neuropsychiatric impairment in Alzheimer disease
Abstract
This cohort study examines the association of serum hyperphosphorylated tau and neurofilament light chain concentrations with psychosis in Alzheimer disease.