PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
January 23, 2026European Heart Journal Open2 citationsOpen Access

Effect of behavioural sleep interventions on blood pressure, heart rate and heart rate variability in adults with poor sleep health: a systematic review, meta-analysis and meta-regression analysis

View Full Paper
SMSAMIUL MOSTAFAUniversity Hospitals Birmingham NHS Foundation TrustWHWasim HanifBirmingham City UniversityGBGeorge M. BalanosUniversity College Birmingham

Key Result

Behavioural sleep interventions reduced systolic blood pressure by an average of 5.02 mmHg and diastolic blood pressure by 2.90 mmHg in adults with poor sleep health.

Key Points

  • The aim is to determine how behavioral sleep interventions affect cardiovascular risk factors like blood pressure and heart rate in adults with poor sleep health.
  • Conducted literature searches on multiple databases including MEDLINE and Cochrane Library.
  • Included studies with adults 18 years and older, featuring sleep interventions and pre- and post-risk factor measurements.
  • Excluded studies focusing on obstructive sleep apnoea.
  • Performed meta-analyses and meta-regression on the gathered data.
  • Significant reduction in systolic blood pressure averaging 4.91 mmHg compared to control in meta-analysis of 12 RCTs.
  • Combined analysis showed reductions in systolic blood pressure of 5.02 mmHg and diastolic blood pressure of 2.90 mmHg.
  • Cognitive behavioural therapy and sleep hygiene interventions resulted in SBP decrease of 3.44 mmHg.
  • Sleep extension interventions led to a 7.59 mmHg reduction in SBP and improvements in DBP and HR.
  • No significant changes in heart rate variability were noted.

Structured PICO

Do behavioural sleep interventions reduce blood pressure, heart rate, and heart rate variability in adults with poor sleep health?

P
Population
21 studies pooling 1,222 adults ≥ 18 years with poor sleep health (excluding obstructive sleep apnoea)
I
Intervention
Behavioural sleep interventions, specifically Cognitive Behavioural Therapy for Insomnia (CBT-I), sleep hygiene, and/or sleep extension
C
Comparator
Control group
O
Outcome
Changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and heart rate variability (HRV)surrogate

Behavioural sleep interventions, including CBT-I and sleep extension, yield clinically significant reductions in blood pressure, suggesting they could be a valuable component of blood pressure management.

Abstract

Abstract Background Poor sleep health is known to negatively impact on cardiovascular risk factors, including systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR) and heart rate variability (HRV). Consequently, there is interest in determining the impact of improving sleep on cardiovascular risk. We reviewed studies aimed at improving sleep using (1) Cognitive Behavioural Therapy for Insomnia (CBT-I) and/or sleep hygiene and (2) sleep extension on these risk factors. Methods Literature searches were performed on MEDLINE, EMBASE, CINAHL and Cochrane Library. Studies featuring adults ≥ 18years, a sleep intervention and pre- and post-risk factor measurements available were included. Studies of obstructive sleep apnoea were excluded. Results From 21 studies (n = 1222), meta-analyses of 12 RCTs (n = 688), demonstrated a significant reduction in SBP averaging 4.91 mmHg (2.38, 7.43, p 0.00001, heterogeneity (I2) = 74%), compared to control. When 15 RCTs and non-RCTs were combined (n = 860), reductions in SBP and DBP averaged 5.02 mmHg (95% CI 2.80, 7.23, p 0.00001, I2 67%) and 2.90 mmHg (0.30, 5.49; p = 0.03, I2 88%) respectively. In eight CBT-I and/or sleep hygiene interventions (n = 618), the SBP decrease averaged 3.44 mmHg (1.07, 5.80, p = 0.004). In sleep extension interventions (n = 242; 7 studies), reductions in SBP averaged 7.59 mmHg (4.74, 10.44; p 0.00001), DBP 4.83 mmHg (0.73, 8.92; p = 0.02) and HR (n = 164, 4 studies) 1.24 beats/minute (0.44, 2.44; p = 0.04). No significant changes in HRV were observed. Seven studies were of low concern on quality assessment. Conclusions Using behavioural sleep interventions led to clinically significant reductions in blood pressure, suggesting addressing poor sleep health could feature in blood pressure management. Future randomised controlled trials are still required.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

MOSTAFA et al. (2026) studied this question. Behavioural sleep interventions reduced systolic blood pressure by an average of 5.02 mmHg and diastolic blood pressure by 2.90 mmHg in adults with poor sleep health.

synapsesocial.com/papers/69731005c8125b09b0d1fbaahttps://doi.org/10.1093/ehjopen/oeag006
Ask AI
Helpful
Bookmark
Share
View Full Paper