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January 23, 20260 citationsOpen Access

Effectiveness of Acupuncture and Traditional Chinese Medicine in Alzheimer's Disease

Effectiveness and Safety of Acupuncture and Traditional Chinese Medicine in Alzheimer's Disease: A Narrative Review

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Authors

RFRaquel F. M. FradeAAAndreia Almeida

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Overview

Narrative review assesses acupuncture's efficacy and safety in Alzheimer's disease, suggesting promising outcomes.

Key Points

  • To evaluate the efficacy, safety, and biological mechanisms of acupuncture for Alzheimer's disease treatment.
  • Reviewed clinical and preclinical studies on acupuncture, electroacupuncture, and moxibustion
  • Analyzed outcomes in combination with pharmacotherapy like donepezil
  • Examined neuroimaging data from fMRI and PET scans
  • Acupuncture combined with pharmacotherapy showed significantly improved outcomes over drug monotherapy
  • Stimulation at specific points reduced amyloid-beta deposition and enhanced glucose metabolism
  • Neuroimaging indicated increased hippocampal connectivity and blood flow after treatment
  • Minimal mild adverse events confirmed a favorable safety profile

Cite This Study

Frade et al. (2026) studied this question.

synapsesocial.com/papers/69731005c8125b09b0d1fcb6https://doi.org/10.5281/zenodo.18327874
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