Atypical Skull Base Osteomyelitis From Streptococcus parasanguinis

Atypical skull base osteomyelitis is a rare condition that can lead to critical complications if left unrecognized. It is difficult to diagnose owing to nonspecific clinical presentations and delayed imaging findings. It typically occurs from nonotologic infections that affect the clivus and requires at least 6 weeks of antibiotics. This case describes a patient presenting with an acute left-sided headache who was eventually diagnosed with atypical skull base osteomyelitis caused by Streptococcus parasanguinis from a sinus infection.