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Assesses HLA expression and immunogenicity in fetal liver-derived cells, suggesting their potential in regenerative medicine.
This study provides the first systematic assessment of HLA expression in fetal liver-derived progenitor and stem cells following cryopreservation. The results suggest that these cells retain a favorable immunological profile, supporting their potential application in regenerative medicine. The findings highlight the importance of considering gestational age in evaluating immunogenicity. Further studies with larger sample sizes and in vivo validation are required to confirm clinical safety.
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Vatlitsov et al. (2026) studied this question.
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