In a cohort of 176 patients with infective endocarditis undergoing surgery in Vietnam, 67.5% had positive blood cultures, primarily identifying Viridans streptococci and Streptococcus spp.
In a Vietnamese cohort, surgical intervention for infective endocarditis demonstrated a low 30-day mortality of 2.8%, highlighting the feasibility and safety of surgery in resource-limited settings.
Absolute Event Rate: 0% vs 0%
Abstract Objectives Infective endocarditis (IE) is a life-threatening infection of the inner lining of the heart resulting in severe complications such as valvular destruction and systemic embolism. Surgical intervention is often required to manage advanced cases. This study describes the clinical, paraclinical, and microbiological characteristics of patients with IE undergoing valve surgery at a tertiary cardiovascular centre in a developing country. Methods This retrospective study analysed 176 patients with IE who underwent valve surgery at a single centre in Vietnam between January 2019 and December 2023. Results The mean age of the cohort was 43.6 ± 15.9 years, with 62.5 % male patients and 13.5 % having a history of cardiac surgery. Mitral valve involvement was the most common lesion (94.9 %), predominantly presenting as regurgitation (96.4 %). The mean white blood cell count was 10.3 ± 8.6 K/μL, indicating an inflammatory response. Blood cultures were positive in 67.5 % of cases, with Viridans streptococci (34.6 %) and Streptococcus spp. (34.6 %) being the most frequently identified pathogens. Conclusions This study provides comprehensive data on patients with IE undergoing surgery in Vietnam, highlighting the importance of early diagnosis, microbiological identification, and surgical intervention for improving patient outcomes in resource-limited settings.
Anh et al. (Thu,) 报道了一项其他研究。在越南接受手术的 176 例感染性心内膜炎患者队列中，67.5% 存在血培养阳性，主要鉴定出 Viridans streptococci 和 Streptococcus spp.。