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Synapse
January 24, 20268 citations

Risk-weighted apoB: a novel summary metric outperforming traditional lipid biomarkers in predicting coronary heart disease.

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BMB. Rehman MichaelaEBElias BjörnsonMAMartin Adiels

Key Points

  • To evaluate the effectiveness of risk-weighted apoB in predicting coronary heart disease compared to traditional lipid biomarkers.
  • Analysis of risk-weighted apoB considering particle number and atherogenicity
  • Comparison with conventional lipid biomarkers
  • Evaluation of clinical risk stratification effectiveness
  • Risk-weighted apoB demonstrated superior predictive ability for coronary heart disease
  • Clinically meaningful improvements in identifying high-risk individuals

Abstract

RW-apoB represents not only particle number but also accounts for the higher atherogenicity of TRL and Lp(a). It offers clinically meaningful improvements in CHD risk stratification.

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Cite This Study

Michaela et al. (2026) studied this question.

synapsesocial.com/papers/69746126bb9d90c67120b0b3https://doi.org/10.1093/eurheartj/ehaf1124
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