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Bioinformatics reveals immune signaling roles in oral squamous cell carcinoma progression linked to Candida infection, suggesting new targets for treatments.
The results suggest that immune signaling pathways, particularly cytokine-mediated interactions, play a critical role in Candida-mediated progression of OSCC. Chromosomal loci on chromosomes 2, 9, and 16 may harbor key genes involved in this process, potentially serving as targets for future therapeutic interventions. The findings further contribute to a deeper understanding of the immune-mediated mechanisms driving OSCC in the context of Candida infection.
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Shree et al. (2026) studied this question.
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