What question did this study set out to answer?

The study investigates how adhesion affects the rapid recruitment and exclusion of ligands at cell-cell interfaces.

January 25, 2026Nanoscale0 citationsOpen Access

Adhesion-triggered Rapid Recruitment/Exclusion of Membrane-Tethered Ligands at Cell-Cell Interface

YAYusuke Arima HIHiroo Iwata KTKaoru Tamada

Key Points

The study investigates how adhesion affects the rapid recruitment and exclusion of ligands at cell-cell interfaces.
Experimental observation of cell-cell interactions
Analysis of ligand recruitment dynamics
Simulation of membrane environments
Ligand recruitment occurs rapidly upon cell adhesion
Exclusion of certain ligands is observed in crowded membrane environments
Dynamic interactions alter the functionality of cell communication.

Abstract

Various cell-cell interactions are triggered by the binding of ligands to receptors on the cell membrane. This binding occurs effectively within a biological membrane crowded with other types of membrane...

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Cite This Study

Arima et al. (Thu,) studied this question.

synapsesocial.com/papers/6975b1a9feba4585c2d6d3a3 https://doi.org/https://doi.org/10.1039/d5nr03670d