Demonstrates the structural basis for glycoform selectivity in prion strains, suggesting implications for understanding prion diseases.
Prion diseases originate from the pathological misfolding of the cellular sialoglycoprotein prion protein (PrP C ), universally found across mammalian species, into an aberrant conformation termed PrP Sc , which exhibits high aggregation propensity...
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Francesca Peccati (2026) studied this question.
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