What question did this study set out to answer?

The research aims to explore tungsten-catalyzed hydroboration of N-heteroarenes to improve regioselectivity and yield.

January 25, 2026

Electronically and Sterically Varied Tungsten Carbonyls Applied to the Selective Dearomatization of N-Heteroarenes

PBP. BaiJiangsu University of Science and Technology YLYuzan LiuJiangsu University of Science and Technology LFLi FangJiangsu University of Science and Technology

Puntos clave

The research aims to explore tungsten-catalyzed hydroboration of N-heteroarenes to improve regioselectivity and yield.
Utilized tungsten(0) carbonyl complexes as catalysts.
Employed HBpin for hydroboration.
Conducted reactions under solvent-free conditions.
Analyzed yields of N-boryl-1,2-dihydropyridines.
Achieved up to 99% yield of N-boryl-1,2-dihydropyridines.
Demonstrated complete regioselectivity in reactions.
Highlighted the efficiency of tungsten catalysts for this transformation.

Resumen

We report the first tungsten-catalyzed regioselective 1,2-hydroboration of N-heteroarenes using tunable W(0) carbonyl complexes. Catalyst W-1 enables solvent-free reactions with HBpin, delivering N-boryl-1,2-dihydropyridines in up to 99% yield with complete...

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