Key result
Personal noise exposure linked to increased ST-segment depression risk, enhanced by temperature extremes.
Why the study?
It was unknown whether noise and nonoptimum temperature exposures are linked to myocardial ischemia, either separately or jointly.
Do short-term personal exposures to noise and nonoptimum temperatures increase the risk of ST-segment depression events in generally healthy middle-aged and elderly individuals?
Do short-term personal exposures to noise and nonoptimum temperatures increase the risk of ST-segment depression events in generally healthy middle-aged and elderly individuals?
Short-term exposure to noise and nonoptimum temperatures independently and synergistically increases the risk of myocardial ischemia (ST-segment depression) in healthy older adults.
Answers are grounded in this paper and cite their sources.
Short-term noise and temperature exposures were associated with ST-segment depression in older adults; hypothesis-generating and leaves open causal effects or mitigation strategies.
It remains unknown whether noise and nonoptimum temperature exposures are linked to myocardial ischemia, either separately or jointly. We conducted a multicenter panel study with 24 h real-time personal measurements among generally healthy middle-aged and elderly individuals to investigate potential effects of short-term personal exposures to noise and temperature on ST-segment depression event (STDE) and whether the effects of noise are modified by temperature and vice versa. Generalized linear mixed-effect model and stratified analyses were used. A total of 117 eligible participants completed 256 person-visits. We found increased risks of STDE associated with personal noise exposure and U-shaped exposure-effect relationships between personal temperature exposure and risks of STDE, both occurring over minutes to hours. The nonoptimum temperatures, including low and high temperatures, significantly enhanced the adverse effects of noise on STDE. Significant effect modifications on temperature-related STDE risk by noise were found in both the low and high temperature ranges. Exploratory analyses suggested that decreases in heart rate variability variables, reflecting autonomic imbalance, may explain exposure-related STDE occurrence. Our study identified the independent effects and two-way effect modifications of personal noise and temperature exposures on STDE risk, providing novel insights into the pathways linking these environmental factors to adverse cardiovascular outcomes.
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Wang et al. (2026) studied this question. Personal noise exposure significantly increased the risk of ST-segment depression, with temperature extremes enhancing this effect.
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