What question did this study set out to answer?

To evaluate the effect of probiotic supplementation on developmental progress in healthy preschool-aged children.

January 25, 2026Open Access

Probiotics and developmental progression in healthy preschool-aged children: a double-blind, placebo-controlled trial

Key Points

To evaluate the effect of probiotic supplementation on developmental progress in healthy preschool-aged children.
Conducted a double-blind, placebo-controlled trial
Involved healthy preschool-aged children
Measured developmental progress as the primary outcome
Compared results between probiotic and placebo groups
Probiotic supplementation did not significantly influence developmental progress
Study was determined to be underpowered for its primary outcome
Recommendations for larger studies with diverse populations were made

Abstract

This first-of-its-kind study conducted among healthy preschoolers concludes that probiotic supplementation did not significantly influence developmental progress. However, the study was underpowered for its primary outcome. Future large-scale studies involving diverse populations are recommended.Trial registration: Australian New Zealand Clinical Trials Registry identifier: ACTRN12622000153718..

Probiotics and developmental progression in healthy preschool-aged children: a double-blind, placebo-controlled trial

Key Points

Abstract

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