Assessing in-hospital mortality risk in ICU lung cancer patients using machine learning: An analysis based on the MIMIC-IV database.

The XGBoost-based model showed the best performance in predicting in-hospital mortality among critically ill lung cancer patients. Hospital stay duration and SAPS II score emerged as the most influential predictors,which can serve as the basis for a simplified clinical risk score. These findings may support early risk stratification and guide clinical decision-making in the ICU. The analysis, relying exclusively on internal divisions from MIMIC-IV, restricts the model's generalizability and, consequently, its applicability in broader clinical contexts.