Content validity of two preference-based measures is compared in retinitis pigmentosa, suggesting improvements for better accuracy.
While the EQ-5D-5L and HUI include some content relevant to people with (XL)RP, both instruments appear to be missing concepts that are specifically relevant to this patient population, which could limit content validity and sensitivity to disease severity. Therefore, it may be useful to consider alternative methods for estimating utilities associated with (XL)RP.
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Matza et al. (2026) studied this question.
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