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January 26, 2026Biomaterials Science7 citationsOpen Access

Translational Roadmap of BBB-Targeted Nanoparticle Strategies for Neuroregenerative Therapy in Neurodegenerative Diseases

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SLSohui LeeJLJiyeon LeeKLKangwon Lee

Key Points

  • To explore nanoparticle strategies that can effectively facilitate neuroregeneration in neurodegenerative diseases.
  • Review of current nanoparticle interventions
  • Analysis of blood-brain barrier targeting mechanisms
  • Identification of neuroregenerative pathways
  • Nanoparticles can successfully traverse the blood-brain barrier
  • Targeted approaches show greater efficacy in neuroregeneration
  • Specific neuroregenerative therapies improve outcomes in neurodegenerative models

Abstract

Neuroregeneration has drawn scientific attention due to its therapeutic potential for neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and traumatic brain injury (TBI). A...

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Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6977032e722626c4468e8370https://doi.org/10.1039/d5bm01582k
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