Randomized clinical trial shows ozone injection enhances recovery in lumbar disc herniation, suggesting a new pain relief mechanism.
Targeted periradicular ozone injection is a safe and effective adjunct to PELD, enhancing outcomes in LDH patients. A concentration of 30 µg/ml ozone yielded superior early recovery. The authors' findings suggest that pain relief is mediated through ferroptosis suppression, unveiling a novel therapeutic mechanism for ozone therapy.
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Wang et al. (2026) studied this question.
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