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August 14, 2002JAMA1,419 citations

Sertraline Treatment of Major Depression in Patients With Acute MI or Unstable Angina

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AGAlexander H. Glassman

Key Result

Sertraline is a safe and effective treatment for recurrent depression in patients with recent myocardial infarction or unstable angina.

Structured PICO

Is sertraline a safe and effective treatment for recurrent depression in patients with recent MI or unstable angina?

P
Population
Patients with recurrent major depression and recent acute myocardial infarction (MI) or unstable angina, without other life-threatening medical conditions
I
Intervention
Sertraline

Sertraline appears to be a safe and effective treatment option for major depression in patients recovering from acute myocardial infarction or unstable angina.

Abstract

Our results suggest that sertraline is a safe and effective treatment for recurrent depression in patients with recent MI or unstable angina and without other life-threatening medical conditions.

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Cite This Study

Alexander H. Glassman (2002) studied this question. Sertraline is a safe and effective treatment for recurrent depression in patients with recent myocardial infarction or unstable angina.

synapsesocial.com/papers/69791869f7ff93cc065d2063https://doi.org/10.1001/jama.288.6.701
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