Collaborative care management improved glycated hemoglobin levels by 0.58% and reduced LDL cholesterol levels by 6.9 mg/dl compared to usual care, with significant improvements in systolic blood pressure and depression scores.
RCT (n=214)
Single-blind
Permuted block randomization
Yes
Does a nurse-led collaborative care intervention improve control of medical disease and depression in patients with poorly controlled diabetes, coronary heart disease, or both and coexisting depression?
A primary care-based collaborative care intervention significantly improved both depression and medical disease control (HbA1c, LDL, and systolic blood pressure) in patients with coexisting depression and poorly controlled diabetes or coronary heart disease.
Effect estimate: null (95% CI null)
p-value: p=<0.001
As compared with usual care, an intervention involving nurses who provided guideline-based, patient-centered management of depression and chronic disease significantly improved control of medical disease and depression. (Funded by the National Institute of Mental Health; ClinicalTrials.gov number, NCT00468676.).
Katon et al. (2010) conducted an RCT in Depression and chronic illnesses (diabetes and coronary heart disease) (n=214). Collaborative care management vs. Usual care was evaluated on Improvement in glycated hemoglobin, LDL cholesterol, systolic blood pressure, and SCL-20 depression scores (null, 95% CI null, p=<0.001). Collaborative care management improved glycated hemoglobin levels by 0.58% and reduced LDL cholesterol levels by 6.9 mg/dl compared to usual care, with significant improvements in systolic blood pressure and depression scores.