Optimising response assessment to neoadjuvant therapy in rectal cancer to reduce the incidence of ypT0N0 resection

Key Points

• The aim is to enhance the assessment of patient responses to neoadjuvant therapy in rectal cancer to minimize unnecessary resections.
• Examined the discordance of clinical assessments in ypT0N0 patients.
• Evaluated the impact of improved management decisions based on assessment concordance.
• Management decisions informed by concordant investigations could decrease ypT0N0 resections.
• Improved assessment strategies may lead to better treatment outcomes with less overtreatment.