Risk score for lower-limb amputation and its ability to predict major kidney and cardiovascular events in people with type 1 diabetes

Key Points

• To assess the effectiveness of a 10-year risk score in predicting lower-limb amputation and related major health events in individuals with type 1 diabetes.
• Developed a risk score based on clinical and demographic factors.
• Evaluated the predictive ability of the score over a 10-year period.
• Identified outcomes including lower-limb amputation, kidney failure, and cardiovascular disease.
• The risk score effectively identifies individuals at high risk for lower-limb amputation.
• It also shows excellent predictive ability for kidney failure and cardiovascular disease.
• Individuals identified as high-risk may benefit from targeted preventive measures.