Transparent, 3D-printed microneedle patches that co-deliver ALA and guide blue light for preclinical photodynamic therapy of acne

Key Points

• The aim is to evaluate the efficacy of 3D-printed microneedles delivering ALA and blue light in treating acne.
• Utilized 3D printing technology to create microneedles.
• Implemented photodynamic therapy (PDT) with ALA and blue light.
• Conducted preclinical trials to assess treatment effectiveness.
• Demonstrated effective penetration of ALA into skin layers.
• Observed significant reduction in acne lesions after treatment.
• Showed promising results for photodynamic therapy in acne management.