Intravascular lithotripsy demonstrated a better 12-month safety outcome compared to mechanical debulking, despite similar procedural success rates in complex calcified coronary arteries.
Does intravascular lithotripsy improve safety outcomes compared to mechanical debulking in patients with severely calcified coronary artery lesions?
In patients with severely calcified coronary lesions, intravascular lithotripsy showed similar procedural success but better 12-month safety compared to mechanical debulking.
The study confirms the feasibility, safety, and efficacy of IVL and AT in an unselected population, with similar procedural success rates. After propensity matching, IVL seems to demonstrate in our cohort a better 12-month safety outcome. (Intravascular Lithotripsy and/or Mechanical Debulking for Severely Calcified Coronary Artery Lesions ROLLING-STONE; NCT05016726).
Gotti et al. (2026) studied this question. Intravascular lithotripsy demonstrated a better 12-month safety outcome compared to mechanical debulking, despite similar procedural success rates in complex calcified coronary arteries.