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January 29, 2026JACC AdvancesOpen Access

Automated Abdominal Aortic Calcification Scores and Atherosclerotic Cardiovascular Disease in the UK Biobank Imaging Study

Marc Sim J. Webster Cassandra Smith Afsah Saleem Syed Zulqarnain Gilani Carlos J. Toro-Huamanchumo David Suter Gemma Figtree Anne Karine Lagendijk Emma L. Duncan Carl Schultz Pawel Szulc Joseph Hung Wai H. Lim Samir Raza Nicola P. Bondonno Richard Woodman Jonathan M. Hodgson Douglas P. Kiel Richard L. Prince William D. Leslie John P. Kemp Nicholas C. Harvey John T. Schousboe Joshua Lewis

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Key Points

The research aims to evaluate the effectiveness of automated abdominal aortic calcification scores in screening for atherosclerotic cardiovascular disease.
Utilized machine learning techniques to assess calcification scores on lateral spine images.
Analyzed data from the UK Biobank imaging study to identify risk factors.
Demonstrated that higher calcification scores correlate with an increased risk of atherosclerotic cardiovascular disease events.
Provided evidence for the efficacy of using automated methods for screening.

Implication

Automated screening method identifies higher risk of cardiovascular disease in a population cohort, suggesting improved early detection strategies.

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Cite This Study

Sim et al. (2026) studied this question.

synapsesocial.com/papers/6980fc55c1c9540dea80e23d https://doi.org/10.1016/j.jacadv.2025.102570

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Machine learning for abdominal aortic calcification assessment from bone density machine-derived lateral spine imagescohort · 2023 · 34 citations
2Abdominal Aortic Calcification on Lateral Spine Bone Density Test Images: Potential Role in Cardiovascular Disease Risk Screeningcross-sectional · 2016 · 1 citations
3Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging StudyCross-Sectional Study · 2026
4Long-Term Atherosclerotic Vascular Disease Risk and Prognosis in Elderly Women With Abdominal Aortic Calcification on Lateral Spine Images Captured During Bone Density Testing: A Prospective Studycohort · 2018 · 81 citations
5Abdominal aortic calcification on vertebral morphometry images predicts incident myocardial infarctioncohort · 2009 · 100 citations

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