EBV latency disruption and lytic reactivation are associated with immune dysregulation and immune gene alterations in multiple sclerosis.
Observational
EBV latency disruption and lytic reactivation are associated with immune dysregulation in multiple sclerosis, highlighting potential peripheral biomarkers for disease monitoring.
Our findings support the hypothesis that EBV latency disruption and lytic reactivation contribute to immune dysregulation in MS. The association between EBV transcriptional activity and immune gene alterations may uncover potential peripheral biomarkers of EBV-driven pathology. These molecular signatures may provide insights into novel therapeutic avenues and peripheral biomarkers for MS monitoring.
Meloni et al. (Thu,) conducted a observational in Multiple Sclerosis. EBV latency disruption and lytic reactivation was evaluated on Immune dysregulation and immune gene alterations. EBV latency disruption and lytic reactivation are associated with immune dysregulation and immune gene alterations in multiple sclerosis.