This analysis demonstrates the impact of time-dependent diffusion in a reaction-diffusion equation, suggesting improved modeling for tumor spread.
The paper proposes the analysis of a rather general reaction–diffusion equation in $$(2+1)$$ ( 2 + 1 ) -dimensions with time-dependent coefficients. The novelty brought by our approach refers to the analysis of the equation with the diffusion coefficient as an explicit function of time and the dependent variable. The free derivative term called source will be considered here to be both linear and quadratic in the main variable. The reported results are of twofold importance: (i) for modeling real diffusion phenomena, such as the spread of tumor cells throughout brain tissue; (ii) for investigating mathematical models described by PDEs with variable coefficients in $$(2+1)$$ ( 2 + 1 ) -dimensions, insufficiently studied until now.
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Cimpoiasu et al. (2026) studied this question.
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