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February 2, 2026European journal of medical research1 citationsOpen Access

Biomarkers Linked to Lipid Metabolism and Endoplasmic Reticulum Stress in Pediatric Sepsis

Identification of the biomarkers associated with lipid metabolism and endoplasmic reticulum stress in pediatric sepsis through bioinformatics analysis and quantitative reverse transcriptase PCR (qRT-PCR) assay

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Authors

BSBaoju ShanJCJiaoyang CaoTYTing Yang

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Overview

Bioinformatics analysis identifies biomarkers related to lipid metabolism in pediatric sepsis, suggesting new therapeutic avenues.

Key Points

  • The aim is to identify biomarkers associated with lipid metabolism and endoplasmic reticulum stress in pediatric sepsis.
  • Utilized bioinformatics analysis to identify potential biomarkers.
  • Conducted quantitative reverse transcriptase PCR (qRT-PCR) to validate findings.
  • Identified four key biomarkers: ACER3, DGAT2, GBA, and TSPO.
  • These biomarkers are linked to lipid metabolism and endoplasmic reticulum stress in pediatric sepsis.
  • Findings provide insights into potential treatment strategies for pediatric sepsis.

Cite This Study

Shan et al. (2026) studied this question.

synapsesocial.com/papers/6980fd18c1c9540dea80ed32https://doi.org/10.1186/s40001-026-03931-x
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